药物与靶点

lookup_drug({
  "name": "semaglutide"
})

{
  "summary": "SEMAGLUTIDE (CHEMBL2108724): Protein, max phase 4. mechanisms: Glucagon-like peptide 1 receptor agonist. most reported FAERS terms (spontaneous report counts, not incidence): nausea 10674, off label use 7325, vomiting 6964. FDA label found (boxed warning: yes). Research data lookup only — not medical advice.",
  "records": [
    {
      "title": "SEMAGLUTIDE",
      "url": "https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2108724",
      "source": "chembl",
      "license": "CC BY-SA 3.0",
      "data": {
        "chemblId": "CHEMBL2108724",
        "maxPhase": 4,
        "firstApproval": 2017,
        "mechanisms": [
          {
            "mechanism": "Glucagon-like peptide 1 receptor agonist",
            "action": "AGONIST",
            "targetChemblId": "CHEMBL1784"
          }
        ]
      }
    },
    {
      "title": "FAERS spontaneous adverse event reports mentioning semaglutide",
      "url": "https://open.fda.gov/apis/drug/event/",
      "source": "openfda",
      "data": {
        "totalReports": 73001,
        "reactions": [
          {
            "term": "NAUSEA",
            "reports": 10674
          },
          {
            "term": "OFF LABEL USE",
            "reports": 7325
          },
          {
            "term": "VOMITING",
            "reports": 6964
          }
        ]
      }
    }
  ],
  "credits_used": 1
}